CORD-19:16a812de72963ceda960a168236e8dbe91832d45 / 26854-27493 JSONTXT

{"project":"CORD-19-SciBite-sentences","denotations":[{"id":"T301","span":{"begin":0,"end":639},"obj":"http://www.genenames.org/cgi-bin/gene_symbol_report?match=PRF1"},{"id":"T307","span":{"begin":0,"end":639},"obj":"http://purl.obolibrary.org/obo/HP0011096"},{"id":"T309","span":{"begin":0,"end":639},"obj":"http://purl.obolibrary.org/obo/HP0003470"},{"id":"T314","span":{"begin":0,"end":639},"obj":"DSPEC000027"},{"id":"T317","span":{"begin":0,"end":639},"obj":"https://id.nlm.nih.gov/mesh/D051379"},{"id":"T320","span":{"begin":0,"end":639},"obj":"http://purl.obolibrary.org/obo/GO0030424"},{"id":"T324","span":{"begin":0,"end":639},"obj":"https://id.nlm.nih.gov/mesh/D014777"},{"id":"T328","span":{"begin":0,"end":639},"obj":"https://id.nlm.nih.gov/mesh/D003711"},{"id":"T331","span":{"begin":0,"end":639},"obj":"https://id.nlm.nih.gov/mesh/D009461"},{"id":"T334","span":{"begin":0,"end":639},"obj":"https://id.nlm.nih.gov/mesh/D010243"}],"attributes":[{"id":"A301","pred":"class","subj":"T301","obj":"GENE"},{"id":"A307","pred":"class","subj":"T307","obj":"HPO"},{"id":"A309","pred":"class","subj":"T309","obj":"HPO"},{"id":"A314","pred":"class","subj":"T314","obj":"SPECIES"},{"id":"A317","pred":"class","subj":"T317","obj":"SPECIES"},{"id":"A320","pred":"class","subj":"T320","obj":"GOONTOL"},{"id":"A324","pred":"class","subj":"T324","obj":"INDICATION"},{"id":"A328","pred":"class","subj":"T328","obj":"INDICATION"},{"id":"A331","pred":"class","subj":"T331","obj":"INDICATION"},{"id":"A334","pred":"class","subj":"T334","obj":"INDICATION"}],"text":"Perforin-deficient mice did not acquire hind-limb paralysis, did not show a decrease in spontaneous activity, and did not develop signficant changes in hind-limb stride, suggesting that neurological deficits associated with demyelination are dependent on perforin, and, by extension, on functional cytotoxic T-cells (Murray et al., 1998) . Furthermore, we have recently observed that the number of large axons in the spinal cord does not differ between infected wild-type C57BL/6 mice and perforin-deficient C57BL/6 mice, strengthening the argument that neurological function in these animals is preserved as a result of axon preservation."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T137","span":{"begin":0,"end":339},"obj":"Sentence"},{"id":"T138","span":{"begin":340,"end":639},"obj":"Sentence"}],"text":"Perforin-deficient mice did not acquire hind-limb paralysis, did not show a decrease in spontaneous activity, and did not develop signficant changes in hind-limb stride, suggesting that neurological deficits associated with demyelination are dependent on perforin, and, by extension, on functional cytotoxic T-cells (Murray et al., 1998) . Furthermore, we have recently observed that the number of large axons in the spinal cord does not differ between infected wild-type C57BL/6 mice and perforin-deficient C57BL/6 mice, strengthening the argument that neurological function in these animals is preserved as a result of axon preservation."}

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T137","span":{"begin":0,"end":339},"obj":"Sentence"},{"id":"TextSentencer_T138","span":{"begin":340,"end":639},"obj":"Sentence"},{"id":"TextSentencer_T137","span":{"begin":0,"end":339},"obj":"Sentence"},{"id":"TextSentencer_T138","span":{"begin":340,"end":639},"obj":"Sentence"},{"id":"T64719","span":{"begin":0,"end":339},"obj":"Sentence"},{"id":"T67656","span":{"begin":340,"end":639},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Perforin-deficient mice did not acquire hind-limb paralysis, did not show a decrease in spontaneous activity, and did not develop signficant changes in hind-limb stride, suggesting that neurological deficits associated with demyelination are dependent on perforin, and, by extension, on functional cytotoxic T-cells (Murray et al., 1998) . Furthermore, we have recently observed that the number of large axons in the spinal cord does not differ between infected wild-type C57BL/6 mice and perforin-deficient C57BL/6 mice, strengthening the argument that neurological function in these animals is preserved as a result of axon preservation."}

{"project":"Epistemic_Statements","denotations":[{"id":"T66","span":{"begin":0,"end":339},"obj":"Epistemic_statement"}],"text":"Perforin-deficient mice did not acquire hind-limb paralysis, did not show a decrease in spontaneous activity, and did not develop signficant changes in hind-limb stride, suggesting that neurological deficits associated with demyelination are dependent on perforin, and, by extension, on functional cytotoxic T-cells (Murray et al., 1998) . Furthermore, we have recently observed that the number of large axons in the spinal cord does not differ between infected wild-type C57BL/6 mice and perforin-deficient C57BL/6 mice, strengthening the argument that neurological function in these animals is preserved as a result of axon preservation."}

{"project":"CORD-19-PD-HP","denotations":[{"id":"T63","span":{"begin":50,"end":59},"obj":"Phenotype"},{"id":"T64","span":{"begin":224,"end":237},"obj":"Phenotype"}],"attributes":[{"id":"A63","pred":"hp_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/HP_0003470"},{"id":"A64","pred":"hp_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/HP_0011096"}],"text":"Perforin-deficient mice did not acquire hind-limb paralysis, did not show a decrease in spontaneous activity, and did not develop signficant changes in hind-limb stride, suggesting that neurological deficits associated with demyelination are dependent on perforin, and, by extension, on functional cytotoxic T-cells (Murray et al., 1998) . Furthermore, we have recently observed that the number of large axons in the spinal cord does not differ between infected wild-type C57BL/6 mice and perforin-deficient C57BL/6 mice, strengthening the argument that neurological function in these animals is preserved as a result of axon preservation."}

{"project":"CORD-19-PD-UBERON","denotations":[{"id":"T63","span":{"begin":40,"end":49},"obj":"Body_part"},{"id":"T64","span":{"begin":45,"end":49},"obj":"Body_part"},{"id":"T65","span":{"begin":152,"end":161},"obj":"Body_part"},{"id":"T66","span":{"begin":157,"end":161},"obj":"Body_part"},{"id":"T67","span":{"begin":273,"end":282},"obj":"Body_part"},{"id":"T68","span":{"begin":417,"end":428},"obj":"Body_part"}],"attributes":[{"id":"A63","pred":"uberon_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/UBERON_0002103"},{"id":"A64","pred":"uberon_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/UBERON_0002101"},{"id":"A65","pred":"uberon_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/UBERON_0002103"},{"id":"A66","pred":"uberon_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/UBERON_0002101"},{"id":"A67","pred":"uberon_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/UBERON_2000106"},{"id":"A68","pred":"uberon_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/UBERON_0002240"}],"text":"Perforin-deficient mice did not acquire hind-limb paralysis, did not show a decrease in spontaneous activity, and did not develop signficant changes in hind-limb stride, suggesting that neurological deficits associated with demyelination are dependent on perforin, and, by extension, on functional cytotoxic T-cells (Murray et al., 1998) . Furthermore, we have recently observed that the number of large axons in the spinal cord does not differ between infected wild-type C57BL/6 mice and perforin-deficient C57BL/6 mice, strengthening the argument that neurological function in these animals is preserved as a result of axon preservation."}