Other examples of pathogen products with corresponding TLR-dependence include tri-acyl lipopeptides (TLR1); lipidated peptides, proteins and carbohydrates (TLR2); double-stranded RNA (Poly I:C) (TLR3); flagellin (TLR5); di-acyl lipopeptides (TLR6); and CpG DNA (TLR9) 4 .