What roles do growth factors play in CNS remyelination?

Abstract


The substantial advances that have been made during the last two decades on the developmental biology of the oligodendrocyte lineage have undoubtedly provided a major impetus to the study of CNS remyelination. Specific markers have been recognised that allow the identification of distinctive phenotypes within the oligodendrocyte lineage . Armed with these markers, it has been possible to elucidate the lineage relationships between these phenotypes both in vitro and during de