PubMed:999981
[Effect of hydrocortisone and actinomycin D at different time of the day on incorporation of labeled precursor into the nuclear proteins of intact rat liver].
Vliianie gidrokortizona i aktinomitsina D v raznoe vremia sutok na vkliuchenie mechenogo predshestvennika v iadernye belki intaktnoĭ pecheni krys
Variations in the incorporation of labelled precursor into nuclear rat liver proteins during a day in normal conditions and in the presence of hydrocortisone and actinomycin D are studied. Synthesis of nuclear proteins is found to have a fluctuating character. Hydrocortisone and actinomycin D, injected at different day time, induce changes in the character of nuclear proteins synthesis , which are more pronounced for histones. The effect of the hormone and the antibiotic is tightly bound with the functional state of liver cells at given moment.
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