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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-62 Sentence denotes Alarmin Cytokines as Central Regulators of Cutaneous Immunity.
T2 63-135 Sentence denotes Skin acts as the primary interface between the body and the environment.
T3 136-313 Sentence denotes The skin immune system is composed of a complex network of immune cells and factors that provide the first line of defense against microbial pathogens and environmental insults.
T4 314-459 Sentence denotes Alarmin cytokines mediate an intricate intercellular communication between keratinocytes and immune cells to regulate cutaneous immune responses.
T5 460-707 Sentence denotes Proper functions of the type 2 alarmin cytokines, thymic stromal lymphopoietin (TSLP), interleukin (IL)-25, and IL-33, are paramount to the maintenance of skin homeostasis, and their dysregulation is commonly associated with allergic inflammation.
T6 708-975 Sentence denotes In this review, we discuss recent findings on the complex regulatory network of type 2 alarmin cytokines that control skin immunity and highlight the mechanisms by which these cytokines regulate skin immune responses in host defense, chronic inflammation, and cancer.
T1 0-62 Sentence denotes Alarmin Cytokines as Central Regulators of Cutaneous Immunity.
T2 63-135 Sentence denotes Skin acts as the primary interface between the body and the environment.
T3 136-313 Sentence denotes The skin immune system is composed of a complex network of immune cells and factors that provide the first line of defense against microbial pathogens and environmental insults.
T4 314-459 Sentence denotes Alarmin cytokines mediate an intricate intercellular communication between keratinocytes and immune cells to regulate cutaneous immune responses.
T5 460-707 Sentence denotes Proper functions of the type 2 alarmin cytokines, thymic stromal lymphopoietin (TSLP), interleukin (IL)-25, and IL-33, are paramount to the maintenance of skin homeostasis, and their dysregulation is commonly associated with allergic inflammation.
T6 708-975 Sentence denotes In this review, we discuss recent findings on the complex regulatory network of type 2 alarmin cytokines that control skin immunity and highlight the mechanisms by which these cytokines regulate skin immune responses in host defense, chronic inflammation, and cancer.