Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-62 |
Sentence |
denotes |
Alarmin Cytokines as Central Regulators of Cutaneous Immunity. |
T2 |
63-135 |
Sentence |
denotes |
Skin acts as the primary interface between the body and the environment. |
T3 |
136-313 |
Sentence |
denotes |
The skin immune system is composed of a complex network of immune cells and factors that provide the first line of defense against microbial pathogens and environmental insults. |
T4 |
314-459 |
Sentence |
denotes |
Alarmin cytokines mediate an intricate intercellular communication between keratinocytes and immune cells to regulate cutaneous immune responses. |
T5 |
460-707 |
Sentence |
denotes |
Proper functions of the type 2 alarmin cytokines, thymic stromal lymphopoietin (TSLP), interleukin (IL)-25, and IL-33, are paramount to the maintenance of skin homeostasis, and their dysregulation is commonly associated with allergic inflammation. |
T6 |
708-975 |
Sentence |
denotes |
In this review, we discuss recent findings on the complex regulatory network of type 2 alarmin cytokines that control skin immunity and highlight the mechanisms by which these cytokines regulate skin immune responses in host defense, chronic inflammation, and cancer. |
T1 |
0-62 |
Sentence |
denotes |
Alarmin Cytokines as Central Regulators of Cutaneous Immunity. |
T2 |
63-135 |
Sentence |
denotes |
Skin acts as the primary interface between the body and the environment. |
T3 |
136-313 |
Sentence |
denotes |
The skin immune system is composed of a complex network of immune cells and factors that provide the first line of defense against microbial pathogens and environmental insults. |
T4 |
314-459 |
Sentence |
denotes |
Alarmin cytokines mediate an intricate intercellular communication between keratinocytes and immune cells to regulate cutaneous immune responses. |
T5 |
460-707 |
Sentence |
denotes |
Proper functions of the type 2 alarmin cytokines, thymic stromal lymphopoietin (TSLP), interleukin (IL)-25, and IL-33, are paramount to the maintenance of skin homeostasis, and their dysregulation is commonly associated with allergic inflammation. |
T6 |
708-975 |
Sentence |
denotes |
In this review, we discuss recent findings on the complex regulatory network of type 2 alarmin cytokines that control skin immunity and highlight the mechanisms by which these cytokines regulate skin immune responses in host defense, chronic inflammation, and cancer. |