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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-131 Sentence denotes Endothelial glycocalyx as a critical signalling platform integrating the extracellular haemodynamic forces and chemical signalling.
T2 132-250 Sentence denotes The glycocalyx covers the human mammalian cells and plays important roles in stroke, inflammation and atherosclerosis.
T3 251-340 Sentence denotes It has also been shown to be involved in endothelial mechanotransduction of shear stress.
T4 341-487 Sentence denotes Shear stress induces the remodelling of the major component of the glycocalyx including glypican-1, a cell membrane heparan sulphate proteoglycan.
T5 488-649 Sentence denotes Other factors, such as sphingosine-1-phosphate (S1P), protect the glycocalyx against syndecan-1 ectodomain shedding and induce the synthesis of heparan sulphate.
T6 650-960 Sentence denotes In this study, we reviewed the role of shear stress and S1P in glycocalyx remodelling and revealed that the glycocalyx is a critical signalling platform, integrating the extracellular haemodynamic forces and chemical signalling, such as S1P, for determining the fate of endothelial cells and vascular diseases.
T7 961-1243 Sentence denotes This review integrated our current understanding of the structure and function of the glycocalyx and provided new insight into the role of the glycocalyx that might be helpful for investigating the underlying biological mechanisms in certain human diseases, such as atherosclerosis.
T1 0-131 Sentence denotes Endothelial glycocalyx as a critical signalling platform integrating the extracellular haemodynamic forces and chemical signalling.
T2 132-250 Sentence denotes The glycocalyx covers the human mammalian cells and plays important roles in stroke, inflammation and atherosclerosis.
T3 251-340 Sentence denotes It has also been shown to be involved in endothelial mechanotransduction of shear stress.
T4 341-487 Sentence denotes Shear stress induces the remodelling of the major component of the glycocalyx including glypican-1, a cell membrane heparan sulphate proteoglycan.
T5 488-649 Sentence denotes Other factors, such as sphingosine-1-phosphate (S1P), protect the glycocalyx against syndecan-1 ectodomain shedding and induce the synthesis of heparan sulphate.
T6 650-960 Sentence denotes In this study, we reviewed the role of shear stress and S1P in glycocalyx remodelling and revealed that the glycocalyx is a critical signalling platform, integrating the extracellular haemodynamic forces and chemical signalling, such as S1P, for determining the fate of endothelial cells and vascular diseases.
T7 961-1243 Sentence denotes This review integrated our current understanding of the structure and function of the glycocalyx and provided new insight into the role of the glycocalyx that might be helpful for investigating the underlying biological mechanisms in certain human diseases, such as atherosclerosis.