Cannabis use did not change in times of social isolation. This may indicate a true similarity in the point estimates before and during the lockdown, but it may also reflect a zero net-effect of increased need and reduced availability of cannabis in times of social lockdown (borders are closed, dealers have a harder time to go around unnoticed, and prices increase due to increased demand). Similar to smoking, the top for an increased use of cannabis was boredom. The similarities between ranked motives of cannabis and cigarette smoking are most probably an artefact because most cannabis users are also cigarette smokers. This explains why the ranking of motives is almost the same for smoking cigarettes and cannabis use, and is the result of the fact that no separate questions about motives were asked for the 3 separate substances. It might be an interesting future research question to investigate what drives certain individuals to consume more, less, or equal during a pandemic, and individual assessment of different motives for use, per substance, would here be valuable. Also, focussing on more positive factors might reveal now underreported factors for better resilience and consequently more adequate coping mechanisms than substance use.