Table 7 Coefficient of Determination r2 and Releasing Model Constant K for Drug Releasing Models Model pH 1.2 pH 6.4 Coefficient of determination, r2 Release model constant, K Coefficient of determination, r2 Release model constant, K Zero order 0.6184 3.1424 0.5605 3.0729 First order 0.9339 0.2588 0.7999 1.3440 Higuchi model 0.9341 25.4563 0.9199 26.5229 Korsmeyer-Peppas model 0.3101 18.6351 0.2953 19.8312 Hixson-Crowell model 0.0053 0.0131 0.0032 0.0100 The italicized is done to show the Nanoparticle release model is folloing Higuchi release model. It is done just to make it more visible