Table VI displays the particle size of PALN1 at different sampling time. The t tests were conducted with a p value higher than 0.05 for all tests suggested that there was an insignificant variation in PALN1 particle size on each sampling time as compared with 0th day’s measurement. The obtained results were in agreement with a PALN1 zeta potential of 37.70 ± 1.16 mV which render the suspension stable by avoiding particle aggregation due to strong surface charge that repels each other. In brief, optimised formulations exhibit good physical stability for up to 60 days. There was no significant difference was observed p < 0.05.
Table 6 Particle Size and Zeta Potential of PALNs at Each Sampling Time
Day Particle size (nm) Zeta potential (mV)
0th 187.70 ± 3.75 37.94 ± 0.33
15th 193.80 ± 5.73 38.26 ± 0.40
30th 194.77 ± 2.05 38.22 ± 0.33
45th 184.37 ± 4.00 37.83 ± 0.26
60th 183.47 ± 4.47 37.32 ± 0.29