For the whole group of patients, there was no significant correlation between L/S and ALT or AST that were obtained at hospital admission. However, negative correlations were found between L/S and both ALT and AST at follow-up (r =  − 0.534, p = 0.004 for L/S and ALT; r =  − 0.46, p = 0.016 for L/S and AST). As L/S decreased, both ALT and AST values increased.