Resulting nanoparticle sizes after spray drying of PLGA/PVA double emulsions with and without the addition of different matrix excipients. Spray-dried powders were reconstituted in purified water, then aggregates were removed by filtration, and particle size distribution was measured by dynamic light scattering. Nanoparticles precipitated by solvent displacement without spray drying served as the control. Measurements were done in triplicate, RSD < 0.5%