Studies suggest that there are many differences between men and women in the immune response to SARS-CoV-19, affecting more men than women [9, 10]. Despite our study showed no difference in the clinical presentation of conjunctivitis in male and female, we found that conjunctivitis was more frequent in males with moderate COVID-19 and women with mild disease. We believe this is related to males having a more severe biochemical COVID-19 profile than females.