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0 TIAB COVID-19: from epidemiology to treatment Abstract The COVID-19 pandemic has greatly impacted the dai 1 531 0 show
1 <title>Introduction and scope of the review</title> Case study 1: A 59-year-old male underwent cardiac surgery for complicated prosthetic valve endocard 1 2400 0 show
2 <title>Current epidemiology</title> As of today, the pandemic has undergone three main phases in terms of geographical scope. From late 1 1530 0 show
3 <title>The virus and pathogenesis</title> Coronaviruses are found in a variety of birds and mammals throughout the world and have a proclivity 1 3131 0 show
4 <title>Pro-inflammatory and pro-coagulant states as triggers of cardiovascular events</title> ACE2 receptors are also located in the heart, kidney, brain, and gut, and therefore COVID-19 might c 1 1186 0 show
5 <title>Clinical manifestations</title> The most common symptoms of COVID-19 are fever and dry cough, together with shortness of breath (Tab 1 2071 0 show
6 <title>Clinical manifestations</title> Cardiovascular manifestations Table 3 shows a summary of the cardiovascular manifestations and compl 1 1992 0 show
7 <title>Diagnosis</title> Laboratory diagnosis is a priority for clinical management and outbreak control of COVID-19. Respira 1 1243 0 show
8 <title>Prognosis focused on cardiovascular risk factors</title> Older age is the most widely recognized epidemiological risk factor of mortality (Table 4). Mortalit 1 2125 0 show
9 <title>COVID-19 treatment and cardiovascular drugs</title> Currently there are no approved therapies specific to human coronavirus, and multiple medical counte 1 6640 0 show
10 <title>Prevention adapted to Cardiology and Cardiovascular Surgery</title> Once a first imported case of COVID-19 is confirmed and isolated, the potential for further exponent 1 4206 0 show
11 <title>Prevention adapted to Cardiology and Cardiovascular Surgery</title> The operating room and the catheterization/electrophysiology labs Case study 3: A 65-year-old male w 1 2552 0 show
12 <title>Prevention adapted to Cardiology and Cardiovascular Surgery</title> Special considerations for management of cardiovascular emergencies in confirmed or suspected COVID- 1 1365 0 show
13 <title>Prevention adapted to Cardiology and Cardiovascular Surgery</title> Burdens of operability in a COVID-19 environment The burdens of cardiac operability, procedural choi 1 1137 0 show
14 <title>Prevention adapted to Cardiology and Cardiovascular Surgery</title> Allocation of resources and service preservation in cardiovascular departments Care for non-COVID-19 1 1821 0 show
15 <title>Prevention adapted to Cardiology and Cardiovascular Surgery</title> Reintroducing cardiovascular services after COVID-19 Once the peak of COVID-19 is overcome in a part 1 660 0 show
16 <title>Conclusions</title> The COVID-19 pandemic is largely and rapidly affecting daily clinical practice, and cardiologists an 1 1328 0 show
17 Caption-Table 1 Summary of the epidemiology of COVID-19 in the top 10 European countries 1 72 0 show
18 Caption-Figure 1 Life cycle of SARS-CoV-2 and potential medical countermeasures. The positive-sense RNA genome of SAR 1 1797 0 show
19 Caption-Figure 2 Clinical stages of COVID-19 (adapted with permission from Siddiqu and Mehra125). During the first da 1 911 0 show
20 Caption-Table 2 Summary of clinical and imaging manifestations of COVID-19 1 58 0 show
21 Caption-Table 3 Cardiovascular manifestations in COVID-19 1 41 0 show
22 Caption-Table 4 Summary of studies assessing prognostic factors of mortality and complications in COVID-19 1 90 0 show
23 Caption-Table 5 Overview of drugs used for COVID-19 treatment 1 45 0 show
24 Caption-Figure 3 Proposed scheme of prevention measures in different settings involving cardiovascular patients durin 1 203 0 show
25 Caption-Figure 4 Proposed organization of an ICU during the COVID-19 pandemic (see text for explanation). FFP3, filte 1 164 0 show