Variable Unadjusted OR (95% CI) p-value Adjusted OR (95% CI) p-value# Demographic characteristic  Age 1.02 (1.00–1.04) 0.04 1.03 (1.00–1.05) 0.03  Age ≥50 years 2.13 (1.02–4.44) 0.04 2.26 (1.07–4.78) 0.03  Male sex 0.71 (0.34–1.46) 0.35 0.60 (0.28–1.28) 0.19 Comorbidity  Current smoking 0.86 (0.23–3.18) 0.82  Hypertension 0.63 (0.28–1.42) 0.26  Cardiac disease 1.41 (0.30–6.57) 0.67  Diabetes 2.60 (0.64–10.59) 0.18 Drug treatment  Corticosteroid 0.90 (0.44–1.85) 0.78 0.80 (0.38–1.70) 0.57  Lack of lopinavir/ritonavir 2.59 (1.19–5.62) 0.02 2.42 (1.10–5.36) 0.03