Evidence links COVID-19 to variable degrees of inflammation. Corticosteroids offer a potent anti-inflammatory option. However, they do not dictate precise actions and might cause suppression of anti-viral immune responses as well. Studies show that the use of corticosteroids might accelerate recovery from COVID-19. There are no controlled clinical trials that show whether the use of corticosteroids can reduce COVID-19-related death. Moreover, the pro-inflammatory cytokine IL6 is the best-documented cytokine in COVID-19 correlated with severity, criticality, viral load, and prognosis of patients with COVID-19. Tocilizumab, a monoclonal antibody against IL6, could confer clinical benefit in patients with high IL6 levels.