A comparative experimental study was carried out on three different types of synthetic prostheses commonly used for the repair of incisional hernias. A low weight polypropylene mesh was used with no non-stick barrier and two tissue-separating meshes, a light polypropylene composite associated with polyglecaprone and the other a polyester composite with porcine collagen. All meshes were implanted intraperitoneally aiming an analysis of the extent and intensity of adhesions formed between the mesh and the intra-abdominal anatomical structures determined by the three different types of prostheses.