The involvement of central sectors of the mesh by adhesions with the viscera and intra-abdominal structures was statistically significant (p value=0.003) for the mesh composed exclusively of polypropylene compared to the tissue-separating meshes (polypropylene/polyglecaprone and polyester/porcine collagen), which did not show any differences between them. It was evident that this central sector is not compromised in double-sided meshes, where the visceral layer of the mesh is intact and was not compromised by the prosthesis section during the experiment. In fact, most meshes separating implanted tissues did not show adhesions in the central sector of the mesh. This behavior was credited to the presence of the tissue-separating mesh on the visceral surface of the double-sided mesh, which effectively prevented adhesions from appearing. Although the use of tissue separating meshes reduces the probability of adhesions, this was not able to neutralize the appearance of adhesions completely.