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PMC:509410 JSONTXT

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div. section text # proj. length # Ann.
0 TIAB Regulation of Muscle Fiber Type and Running Endurance by PPARδ Endurance exercise training can promo 4 1070 270 show
1 Introduction Skeletal muscle fibers are generally classified as type I (oxidative/slow) or type II (glycolytic/fa 4 2890 803 show
2 Results Activation of PPARδ Leads to Muscle Fiber Transformation A role of PPARδ in muscle fiber was suggest 4 4346 1276 show
3 Results Muscle Fiber Switch by PPARδ Protects Against Obesity A number of previous studies have shown that o 4 1808 479 show
4 Results Activation of PPARδ Enhances Physical Performance Muscle oxidative capacity is a crucial factor for 4 1815 415 show
5 Discussion Our data reveal that a PPARδ-mediated transcriptional pathway can regulate muscle fiber specificatio 4 4460 1096 show
6 Materials and Methods Animals. The transactivation domain (78 amino acid residues, corresponding to residues 413–490) of V 4 1075 341 show
7 Materials and Methods Gene expression analysis and physiological studies Mouse EST clones were obtained from ATCC (Manassa 4 785 194 show
8 Materials and Methods Muscle fiber typing and mitochondrial DNA isolation Muscle fiber typing was essentially performed us 4 297 87 show
9 Materials and Methods Statistical analysis Number of mice for each group used in experiments is indicated in figure legend 4 200 47 show
10 Caption-Figure 1 Expression of Endogenous PPARδ and VP16-PPARδ Transgene in Muscle (A) Pooled RNA isolated from vario 4 872 296 show
11 Caption-Figure 2 Increased Oxidative Type I Fibers in the Transgenic Mice (A and B) Muscles in transgenic mice (TG) a 4 241 89 show
12 Caption-Figure 3 Activation of PPARδ Induces Genes Typical for Type I Fibers and Promotes Mitochondrial Biogenesis (A 4 1118 339 show
13 Caption-Figure 4 Resistance to High-Fat-Induced Obesity in the Transgenic Mice (A) Seven-week-old transgenic (TG) and 4 835 278 show
14 Caption-Figure 5 PPARδ Agonists Counteract Obesity Induced by High-Fat Diet (A) Eleven-week-old wild-type C57B6 mice 4 837 265 show
15 Caption-Figure 6 PPARδ Regulates Exercise Endurance (A) Enhanced exercise performance in the transgenic mice. Fourtee 4 512 148 show