The genomic DNA sequences corresponding to the orthologous TACC genes of human, mouse, rat, pufferfish, C. intestinalis, D. melanogaster and C. elegans were extracted and analyzed by Genescan and BLAST to determine the genomic structure of each TACC gene. In some cases, for rat and pufferfish, exons were added or modified based on the best similarity of translated peptides to the corresponding mouse and human proteins. For regions with low sequence similarity in T. rubripes, genomic sequences  from the fresh water pufferfish, Tetraodon nigroviridis were used as additional means to verify the predicted exons.