(C) Immunohistochemical analysis of YAP, the endothelial cell marker CD31, cleaved caspase 3, and phosphorylated histone H3 in GFP-SmoA1 (top) and YAP-SmoA1 (bottom) medulloblastomas. YAP-SmoA1 tumors have significantly reduced apoptosis and increased proliferation compared with GFP-SmoA1 tumors, indicated in the graphs.