The work was supported by the grant RO1 DK 047995 from NIH/NIDDK to A. Chen Disclosures Section: The authors have nothing to disclose. Abbreviations α-SMA alpha-smooth muscle actin CTGF connective tissue growth factor DMEM Dulbecco's modified Eagle's medium EGFR epidermal growth factor receptor FBS fetal bovine serum GAPDH glyceraldehyde-3-phosphate dehydrogenase HSCs hepatic stellate cells LDL low-density lipoprotein LOX-1 lectin-like oxidized LDL receptor-1 NAFLD nonalcoholic fatty liver disease NASH non-alcoholic steatohepatitis ox-LDL oxidized low-density lipoprotein PDGF-βR platelet-derived growth factor-beta receptor TGF-βR transforming growth factor-beta receptor