PMC:2195754 (8) JSONTXT < >
IκBα defects in HL. The structure of the IκBα gene (top; the amplified regions spanning exons 1–6 are bold, and translation start and stop codons are given) is correlated with the structure of the IκBα protein (bottom; the six ankyrin repeats and the PEST domain are indicated). The positions of the mutations detected in H/RS cells of primary cases, as well as those detected in cell lines, are shown.
|Unselected / annnotation||Selected / annnotation|