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Caption-Figure 1
IκBα defects in HL. The structure of the IκBα gene (top; the amplified regions spanning exons 1–6 are bold, and translation start and stop codons are given) is correlated with the structure of the IκBα protein (bottom; the six ankyrin repeats and the PEST domain are indicated). The positions of the mutations detected in H/RS cells of primary cases, as well as those detected in cell lines, are shown.

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