The authors want to thank Troy Margrie and Bert Sakmann for support, encouragement, and discussion; Onyeka Nobuka for help with the construct OCN; Mark Mayford for the αCaMKII promoter; Bettina Suchanek for the NR2C silencer; Annette Herold, Juliana Kling, and Christiane Zacher for experimental and technical supports; Nixon Abraham for assistance with some behavioral experiments; and David Bannerman, Thomas Kuner, and Pavel Osten for critically reading early versions of the manuscript. This work was supported by a Deutsche Forschungsgemeinschaft grant (SFB 636) to RS, the Heidelberger Akademie der Wissenschaften, the Boeringer Ingelheim Fonds, and the Leopoldina Akademie der Wissenschaften to ATS, the BMBF, and the MPG. Competing interests. The authors have declared that no competing interests exist.