Table 1 Comparison of liver gene expression for pI–pC-induced Mtf1Mx-cre and Mtf1loxP mice (up- or downregulation at least 2-fold, P ≤ 0.05) The animals had obtained either mock s.c. injections (−Cd) or s.c. injections with 20 µmol/kg body weight CdSO4 (+Cd) 6 h before sacrificing them. The expression values for each gene are given as mean value of three animals per group, normalized to the mean value of group Mtf1loxP −Cd (relative activity). Grey shading indicates the two groups of animals compared, relative activities for the other two groups are shown for a complete overview. The number of MRE core consensus sequences TGCRCNC in a region of 1000 bp upstream from the annotated transcription start is indicated. aOnly incomplete region up to −1000 bp from transcription start is available in database. bMean values of two independent Affymetrix probe sets. cMean value of four independent Affymetrix probe sets.