We thank Sushama Varma for technical assistance. This research was supported by the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center (Oligonucleotide and Transgenic Animal Shared Facilities) grant P30-CA13148, UAB Musculoskeletal Disease and Arthritis Center (Gene Targeting Core Facility) grant P60-AR20614, UAB Clinical Nutrition Research Center grant P30-DK-56336, and by National Institutes of Health grants R01-RR02599 (PAW), T32-RR-07003 (RJT), K01-RR00129 (RJT), RO1-DK45482 (JV), and DK54936 (JV).