HeLa cells were incubated with HPV PsV, while 3HP-β-LG (15 μg/ml) was added at different time points (−0.5, 0, 0.5, 1, 2, 4, 8, 12, 24, and 48 h) to analyze the inhibitory activity. (C) 3HP-β-LG blocked HPV PsV entry by targeting virus.